San Francisco, CA — October 2025 The global forum for interventional cardiology, Transcatheter Cardiovascular Therapeutics (TCT) conference, once again brought together the world’s leading experts in interventional cardiovascular medicine to explore the latest breakthroughs in patient care. As the foremost educational forum organized by the Cardiovascular Research Foundation (CRF), TCT continues to set the stage for data-driven innovation and global collaboration in the treatment of structural heart disease.
At TCT 2025, Products & Features (P&F) joined clinical leaders and innovators to share new findings from several ongoing TricValve® investigations, reflecting the growing global experience with heterotopic transcatheter valve therapy for severe tricuspid regurgitation (TR), along with the innovative AortaSave system, the transcatheter Endo-Bentall solution for combined aortic valve and ascending aorta replacement.
Advancing the Evidence for TricValve®
Across multiple sessions, investigators presented emerging data underscoring TricValve’s role in treating patients who remain at high risk for conventional tricuspid valve repair or replacement.
- Global Insights from the TRICUS Registry
Dr. Philipp Nikolai shared real-world outcomes from the international TRICUS Registry, highlighting procedural safety and sustained improvement in right heart failure symptoms following TricValve implantation. - Early Results from the TRICAV-I Early Feasibility Study
Dr. Rishi Puri presented early feasibility outcomes from the TRICAV-I US study, which evaluated TricValve’s performance in alleviating right heart failure through targeted reduction of caval reflux. - National Experience from the TRV-CHILE Registry
Dr. Alberto Barria shared insights from Chile’s national registry, TRV-CHILE, which reinforced TricValve’s reproducible procedural success and clinical benefit in diverse patient populations. - Complex Case Presentation: TRICAV-I
Brian Whisenant, for Dr. John Thomas Saxon, presented a challenging case from the TRICAV-I study, demonstrating successful TricValve implantation in a patient with multiple pre-existing leads — further supporting the device’s versatility in complex anatomies.
Featuring Innovation
- AortoSave in the Shark Tank Innovation Competition
Dr. Diego Felipe Gaia introduced AortoSave system, a next-generation Endo-Bentall system for combined aortic valve and ascending aorta replacement, demonstrating P&F’s continued commitment to addressing complex structural challenges.
Collaboration and Innovation at the Core
Throughout the meeting, the P&F team connected with clinicians, researchers, and industry partners to exchange perspectives on device design, patient selection, and the expanding ecosystem of tricuspid valve solutions. These conversations underscored a shared commitment to refining minimally invasive therapies that address a growing global need.
Looking Ahead
As clinical experience continues to evolve, P&F remains focused on advancing data-driven innovation and expanding access to transcatheter solutions for right heart disease. The insights shared at TCT 2025 mark another step forward in shaping the next chapter of tricuspid therapy.